Alopecia areata - 円形脱毛症
円形脱毛症 (Alopecia areata) は頭皮の裏側に見られます。典型的な場合、それは突然完全に滑らかな表面で2〜3 cmの大きさで現れます。
relevance score : -100.0%
ReferencesAlopecia areata は、免疫システムが毛包を攻撃し、瘢痕を残さずに一時的な脱毛を引き起こす疾患です。斑点状の脱毛として現れることもあれば、頭皮全体や体全体に広がることもあります。生涯のある時点で約 2% の人に影響します。主な原因は、毛包周囲の自然な保護機能が破壊されることと考えられています。
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata は、免疫システムが毛包を攻撃し、頭皮や体の他の毛深い部位に脱毛を引き起こす症状です。世界中の約 2% の人が罹患しています。どの年齢でも発症する可能性がありますが、成人よりも小児に多く見られます（1.92% vs. 1.47%）。女性、特に 50 歳以上の女性は男性よりもこの症状を経験しやすい傾向があります。コルチコステロイドを局所的に塗布するよりも、患部に直接注射する方が良い結果が得られています。
Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
円形脱毛症は、毛包を標的とした自己免疫疾患と考えられています。根底にあるメカニズムは、自己の毛包細胞を誤って認識し、免疫が毛包を攻撃して破壊することです。
○ 治療 ― OTC医薬品
軽度の場合、治療を行わなくても1年以内に自然回復することがありますが、多くの患者は頭皮の別の部位で再発を繰り返します。
#Hydrocortisone cream
○ 処理
病変内ステロイド注射が最も効果的な治療法です。頭皮の広範囲が影響を受けている場合は、免疫療法を試すことができます。
#Triamcinolone intralesional injection
#DPCP immunotherapy